Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Sep;62(2-3):179-90.
doi: 10.1016/0378-4274(92)90020-k.

Incidence, histopathologic and electron microscopic features of spontaneous nephroblastomas in rats

M Chandra  1 , W W Carlton
Affiliations

Incidence, histopathologic and electron microscopic features of spontaneous nephroblastomas in rats

M Chandra et al. Toxicol Lett. 1992 Sep.

Erratum in

  • Toxicol Lett 1993 Mar;66(3):331-333

Abstract

Primary renal neoplasms in the rats are uncommon. Nephroblastoma is the only renal embryonal tumor of the rat; all other tumors are reported in older rats. The occurrence of spontaneous nephroblastoma in rats has been reported. However, metastasis from the nephroblastoma in rat is extremely rare. Data from 2669 Sprague-Dawley control rats and 1060 Fischer-344 rats were reviewed and evaluated to determine the incidence and pathology of nephroblastoma. This tumor was observed in three Sprague-Dawley rats. Metastasis was observed in the lungs and renal lymph nodes in two different rats. No case of nephroblastoma was observed in Fischer-344 rats. Detailed histopathological and electron microscopic features of these neoplasms are described and discussed.

PubMed Disclaimer

LinkOut - more resources