A method for the quantitative determination of urinary glycosaminoglycans
- PMID: 133005
- DOI: 10.1016/0009-8981(76)90356-9
A method for the quantitative determination of urinary glycosaminoglycans
Abstract
A method is presented by which the urinary glycosaminoglycans can be isolated in a macromolecular fraction with complete recovery by preparative gel filtration. The urinary glycosaminoglycans can be quantitated by determinations of uronic acid and sulfaminohexose in the macromolecular fraction. Using untreated, random urine specimens of less than 5 ml volume, clinical mucopolysaccharidoses types I, II, and III could be readily distinguished.
Similar articles
-
Differentiation of mucopolysaccharidoses by analyses of the excreted sulfated mucopolysaccharides.Clin Chim Acta. 1977 Nov 1;80(3):555-62. doi: 10.1016/0009-8981(77)90150-4. Clin Chim Acta. 1977. PMID: 144036
-
Normalization of glycosaminoglycan-derived disaccharides detected by tandem mass spectrometry assay for the diagnosis of mucopolysaccharidosis.Sci Rep. 2019 Jul 24;9(1):10755. doi: 10.1038/s41598-019-46829-x. Sci Rep. 2019. PMID: 31341247 Free PMC article.
-
Rapid identification of San Filippo disease (MPS III).Health Lab Sci. 1978 Jul;15(3):123-7. Health Lab Sci. 1978. PMID: 151669
-
[Mucopolysaccharidoses].Pediatr Pol. 1976 Jun;51(6):735-47. Pediatr Pol. 1976. PMID: 821035 Review. Polish. No abstract available.
-
Clinicopathological conference: an adolescent girl with severe mental impairment and mucopolysacchariduria.Am J Med Genet. 1985 Sep;22(1):1-27. doi: 10.1002/ajmg.1320220102. Am J Med Genet. 1985. PMID: 2931979 Review. No abstract available.
Cited by
-
Structure, function, and pathology of proteoglycans and glycosaminoglycans in the urinary tract.World J Urol. 1994;12(1):3-10. doi: 10.1007/BF00182044. World J Urol. 1994. PMID: 8012413 Review.
-
Mass spectrometry-based proteomics in neurodegenerative lysosomal storage disorders.Mol Omics. 2022 May 11;18(4):256-278. doi: 10.1039/d2mo00004k. Mol Omics. 2022. PMID: 35343995 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources