Evidence for tachykinin NK-2B-like receptors in guinea-pig alveolar macrophages
- PMID: 1331635
- DOI: 10.1016/0024-3205(92)90626-z
Evidence for tachykinin NK-2B-like receptors in guinea-pig alveolar macrophages
Abstract
Mammalian tachykinins dose-dependently activate guinea-pig alveolar macrophages, by interacting with tachykinin NK-2 receptors, mainly. By evaluating the effects of different NK-2 tachykinin receptor antagonists, we now provide evidence that tachykinin NK-2 receptors in guinea-pig alveolar macrophages meet the pharmacological criteria used to define the NK-2B subtype.
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