doi: 10.1212/wnl.26.8.785.
Brain serotonin after experimental vascular occlusion
- PMID: 133300
- DOI: 10.1212/wnl.26.8.785
Item in Clipboard
Brain serotonin after experimental vascular occlusion
Neurology.
1976 Aug.
Abstract
Unilateral ligation of a common carotid artery in gerbils causes a decreased rate of serotonin synthesis and degradation but an increased release of this monoamine. In the brain, reduction of cerebral serotonin content during ischemia is followed by accumulation of its main metabolite, 5-hydroxyindolacetic acid. These data support the contention that serotonin plays an important role in the progression of cerebral infarction.
Similar articles
-
Serotonin turnover rate in raphe and cortex of mice infected with Venezuelan equine encephalomyelitis virus.J Neurosci Res. 1987;17(4):428-34. doi: 10.1002/jnr.490170415. J Neurosci Res. 1987. PMID: 2442407 Free PMC article.
-
Effect of lithium on brain 5-hydroxytryptamine metabolism in mice.Arch Int Pharmacodyn Ther. 1976 Jul;222(1):116-24. Arch Int Pharmacodyn Ther. 1976. PMID: 136232
-
Metabolism of a tryptophan load in the hypothalamus and other brain regions.J Neurochem. 1975 Sep;25(3):251-6. doi: 10.1111/j.1471-4159.1975.tb06961.x. J Neurochem. 1975. PMID: 125780 No abstract available.
-
The effect of serotonin receptor blocking agents--cyproheptadine and danitracen--on serotonin turnover in the rat brain.Pol J Pharmacol Pharm. 1977 Sep-Oct;29(5):485-95. Pol J Pharmacol Pharm. 1977. PMID: 145590
-
[Role of active transport of 5-hydroxyindoleacetic acid in serotonin metabolism in the brain].Ross Fiziol Zh Im I M Sechenova. 2004 Apr;90(4):490-4. Ross Fiziol Zh Im I M Sechenova. 2004. PMID: 15296070 Review. Russian. No abstract available.
Cited by
-
Study of 5-hydroxytryptamine (serotonin) in pericardial fluid in different causes of death (II.). Experimental study of 5-HT levels in two types of shocks (hemorrhagic and septic) in dogs.Z Rechtsmed. 1983;89(4):227-36. doi: 10.1007/BF00203726. Z Rechtsmed. 1983. PMID: 6404070
-
Cerebral ischemia: changes in monoamines are independent of energy metabolism.Neurochem Res. 1989 Jan;14(1):1-7. doi: 10.1007/BF00969750. Neurochem Res. 1989. PMID: 2469024
-
Cellular basis of anoxic-ischemic brain injury.West J Med. 1978 Jul;129(1):8-18. West J Med. 1978. PMID: 685270 Free PMC article.
-
Monoamines and related enzymes in cerebral cortex and basal ganglia following transient ischemia in gerbils.Acta Neuropathol. 1980;51(1):71-7. doi: 10.1007/BF00688852. Acta Neuropathol. 1980. PMID: 7435143
-
CSF and plasma levels of pro-opiomelanocortin-related peptides in reversible ischaemic attacks and strokes.J Neurol Neurosurg Psychiatry. 1986 Jan;49(1):17-21. doi: 10.1136/jnnp.49.1.17. J Neurol Neurosurg Psychiatry. 1986. PMID: 3007673 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
