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. 1992 Oct;50(4):288-92.

Does Hakka ethnic group have higher incidence of thalassemia traits in Taiwanese population?

Affiliations
  • PMID: 1334786

Does Hakka ethnic group have higher incidence of thalassemia traits in Taiwanese population?

C C Chien et al. Zhonghua Yi Xue Za Zhi (Taipei). 1992 Oct.

Abstract

The purpose of this survey is to find out whether Hakka group has higher incidence of thalassemia traits in our population. A total of 1,115 healthy employees from a company were screened by complete blood count (CBC) with indices. Those subjects with mean corpuscular volume (MCV) less than 80 fl were further evaluated by hemoglobin electrophoresis and modified hemoglobin H (Hb H) inclusion staining to confirm the diagnosis of beta- and alpha-thalassemia traits, respectively. We evaluated and compared the crude occurrence rates of thalassemia traits in Hakka, non-Hakka, and Taiwanese. Subjects with one or both Hakka parents had higher crude incidence of alpha-thalassemia traits than other groups of subjects, but this phenomenon wasn't found in beta-thalassemia traits.

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