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. 1956 Jul 25;2(4 Suppl):157-62.
doi: 10.1083/jcb.2.4.157.

The ultrastructure of striated muscle at various sarcomere lengths

The ultrastructure of striated muscle at various sarcomere lengths

D SPIRO. J Biophys Biochem Cytol. .

Abstract

1. Rest and equilibrium length muscle sarcomeres are composed of thin filaments (actin) which traverse the sarcomeres from the Z membranes up to the H band; at this level the filaments are considerably thicker and less numerous. 2. Shortening of muscle is associated with a transformation of thin into thick filaments in the A band. 3. These observations are discussed in terms of interaction of actin and myosin to form a supercoiled structure as the basis of contraction.

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