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. 1956 Sep 1;104(3):411-8.
doi: 10.1084/jem.104.3.411.

Experimental enteric Shigella and Vibrio infections in mice and guinea pigs

R FRETER

Experimental enteric Shigella and Vibrio infections in mice and guinea pigs

R FRETER. J Exp Med. .

Abstract

A method has been devised for inhibiting the normal enteric flora, permitting long term asymptomatic enteric infections of mice and guinea pigs with streptomycin-resistant strains of Shigella flexneri or Vibrio cholerae. Introduction of a streptomycin-resistant strain of E. coli into the intestinal tract of experimental animals resulted in a rapid elimination of the enteric pathogens studied. No in vitro production of antibiotic substances by this coli strain could be demonstrated. Active and oral passive immunization did not noticeably influence the number of Shigella or Vibrio organisms recoverable from the feces of infected animals.

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References

    1. J Infect Dis. 1953 Mar-Apr;92(2):152-63 - PubMed
    1. J Infect Dis. 1953 Mar-Apr;92(2):164-74 - PubMed
    1. J Infect Dis. 1953 Nov-Dec;93(3):243-6 - PubMed
    1. Proc Soc Exp Biol Med. 1954 May;86(1):132-7 - PubMed
    1. Bull World Health Organ. 1955;12(6):945-1107 - PubMed