Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 May 15;156(2):333-7.
doi: 10.1042/bj1560333.

Control of rat mammary-gland pyruvate dehydrogenase by insulin and prolactin

B Field, H G Coore

Control of rat mammary-gland pyruvate dehydrogenase by insulin and prolactin

B Field et al. Biochem J. .

Abstract

Withdrawal of prolactin or of insulin from the circulation of lactating rats leads, within 3h, to increased inactivation by phosphorylation of mammary-gland pyruvate dehydrogenase. Prolactin may act by priming the tissue to respond directly to normal concentrations of circulating insulin and by this means be responsible for the increased activation of the enzyme during the course of normal lactation.

PubMed Disclaimer

References

    1. Biochem Soc Trans. 1975;3(2):258-61 - PubMed
    1. J Lipid Res. 1965 Jan;6:16-20 - PubMed
    1. Eur J Biochem. 1973 Apr 2;34(1):188-98 - PubMed
    1. Proc Natl Acad Sci U S A. 1969 Jan;62(1):234-41 - PubMed
    1. J Biol Chem. 1974 Nov 25;249(22):7348-57 - PubMed

MeSH terms