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. 1992 Mar 15;112(2):241-5.
doi: 10.1016/0378-1119(92)90383-z.

Rainbow trout p53: cDNA cloning and biochemical characterization

C Caron de Fromentel  1 , F Pakdel, A Chapus, C Baney, P May, T Soussi
Affiliations

Rainbow trout p53: cDNA cloning and biochemical characterization

C Caron de Fromentel et al. Gene. .

Abstract

We have cloned and sequenced the p53-encoding cDNA of rainbow trout (Salmo gairdneri). The encoded product contains the characteristics found in all p53 proteins: (i) the five highly conserved domains, (ii) an acidic N terminus, (iii) a hydrophilic C terminus, and (iv) a penultimate serine residue. Furthermore, we demonstrate that the rainbow trout p53 is able to specifically interact with the SV40 large T antigen.

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