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. 1992 Dec;90(4):467-8.
doi: 10.1007/BF00220480.

Alpha-1-antichymotrypsin variant detected by PCR-single strand conformation polymorphism (PCR-SSCP) and direct sequencing

M Tsuda  1 , Y Sei, M Matsumoto, H Kamiguchi, M Yamamoto, Y Shinohara, T Igarashi, M Yamamura
Affiliations

Alpha-1-antichymotrypsin variant detected by PCR-single strand conformation polymorphism (PCR-SSCP) and direct sequencing

M Tsuda et al. Hum Genet. 1992 Dec.

Abstract

A new mutant alpha-1-antichymotrypsin (variant ACT) was found by polymerase chain reaction single strand conformation polymorphism and direct sequencing. In this variant ACT, two bases (AA) were deleted from codon 391. This resulted in a different amino acid sequence downstream of the deletion point, elongating the peptide chain by 10 amino acids.

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References

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