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Comparative Study
. 1992;33(4):180-6.
doi: 10.1159/000150249.

Comparative sequence analyses of Epstein-Barr virus nuclear antigen-2 and -3B genes of a fresh Epstein-Barr virus-2 isolate

N Inoue  1 , H Kikuta, K Yanagi
Affiliations
Comparative Study

Comparative sequence analyses of Epstein-Barr virus nuclear antigen-2 and -3B genes of a fresh Epstein-Barr virus-2 isolate

N Inoue et al. Intervirology. 1992.

Abstract

The nucleotide sequence of Epstein-Barr virus (EBV) nuclear antigen (EBNA)-2 and EBNA-3B regions of an EBV-2 isolate in Japan was analyzed. The deduced amino acid sequences of EBNA-2 and EBNA-3B of the isolate and a prototype EBV-2 strain AG876 were identical, but the number of the repeated sequence in EBNA-3B was variable as that of IR-3 in EBNA-1. The remarkably well-conserved sequence seems to suggest that the structure of the EBNA-2 and EBNA-3B genes of EBV-2 is crucial for their function in virus replication.

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