Hemagglutinins of Beauveria bassiana strains: the effect of growth conditions on their production

Abstract

Forty strains of Beauveria bassiana were screened for their ability to produce hemagglutinins. It has been found that majority of mycelial extracts but not cultural broth display non specific hemagglutinating activity toward animal and human type AB and A, B, O erythrocytes when microorganisms are cultivated on rich in amino acids media supplemented with saccharose. The formation of hemagglutinins in mycelia is strongly dependent on composition of medium and associated with a production of extracellular lipases, chitinases and amylases. No monosaccharide binding specificity of obtained hemagglutinins toward glucose/mannose, N-acetylglucosamine, N-acetylgalactosamine/galactose, L-fucose and sialic acid was observed.