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Review
. 1992;85(5 Pt 2):481-5.

Molecular properties of the sodium channel: a receptor for multiple neurotoxins

W A Catterall  1 , V Trainer, D G Baden
Affiliations
  • PMID: 1340350
Review

Molecular properties of the sodium channel: a receptor for multiple neurotoxins

W A Catterall et al. Bull Soc Pathol Exot. 1992.

Abstract

Sodium channels are the receptors for more than 10 distinct classes of biological toxins which act at five or more receptor sites. Brevetoxins and ciguatoxins act at neurotoxin receptor site 5. This receptor site is located on the alpha subunit of the sodium channel, and peptide segments in domain IV of that subunit are important in brevetoxin binding.

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