Clinical Trial
Effect of flunisolide on nasal eosinophils and IgE, and symptom score in children with allergic rhinitis
Affiliations
- PMID: 1342898
Item in Clipboard
Clinical Trial
Effect of flunisolide on nasal eosinophils and IgE, and symptom score in children with allergic rhinitis
J Investig Allergol Clin Immunol.
1992 Jul-Aug.
Abstract
We evaluated the effect of treatment with flunisolide nasal spray (100 micrograms/day for 3 months) in 24 children with allergic rhinitis on the following parameters: clinical symptoms, absolute number of peripheral and nasal eosinophils, and total IgE levels in nasal secretion. Therapy with flunisolide induced a significant reduction of clinical symptoms (p < 0.001), nasal eosinophils (p < 0.001) and nasal IgE concentration (p < 0.02), while it did not affect the number of peripheral eosinophils. These results indicate that flunisolide can reduce the allergic inflammation of the nasal mucosa.
Similar articles
-
Allergic rhinitis in children: effects of flunisolide and disodium cromoglycate on nasal eosinophil cationic protein.Clin Exp Allergy. 1997 Mar;27(3):270-6. Clin Exp Allergy. 1997. PMID: 9088653 Clinical Trial.
-
Topical flunisolide treatment of perennial rhinitis: clinical and immunological effects.Allergol Immunopathol (Madr). 1991 Sep-Oct;19(5):194-6. Allergol Immunopathol (Madr). 1991. PMID: 1811415
-
Topical flunisolide treatment of perennial rhinitis: clinical and immunological effects.Allergol Immunopathol (Madr). 1992 May-Jun;20(3):124-6. Allergol Immunopathol (Madr). 1992. PMID: 1414859
-
Topical steroid treatment for allergic rhinitis and allied conditions.Clin Otolaryngol Allied Sci. 1982 Oct;7(5):343-52. doi: 10.1111/j.1365-2273.1982.tb01918.x. Clin Otolaryngol Allied Sci. 1982. PMID: 6756710 Review. No abstract available.
-
Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestion.Am J Respir Med. 2002;1(3):195-200. doi: 10.1007/BF03256609. Am J Respir Med. 2002. PMID: 14720057 Review.