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Review
. 1993:104:61-72; discussion 72-3.

An experimental approach to understanding the genetic and neurobiological basis of alcoholism

T K Li  1 , L Lumeng, W J McBride, J M Murphy
Affiliations
Review

An experimental approach to understanding the genetic and neurobiological basis of alcoholism

T K Li et al. Trans Am Clin Climatol Assoc. 1993.

Abstract

The development and characterization of an animal model to study mechanisms underlying abnormal alcohol-seeking behavior have been described. Raised by genetic means, it demonstrates the importance of genetic factors in this behavior. It has allowed the elucidation of neural pathways and neurotransmitter systems that subserve alcohol-seeking behavior. It offers the potential for screening new medications for the treatment of alcoholism, based upon these kinds of newly discovered knowledge.

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