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. 1957 Sep;12(3):320-2.
doi: 10.1111/j.1476-5381.1957.tb00141.x.

The enzymatic hydrolysis of imidazoleacryloylcholine (murexine) and imidazolepropionylcholine (dihydromurexine) by various cholinesterases

The enzymatic hydrolysis of imidazoleacryloylcholine (murexine) and imidazolepropionylcholine (dihydromurexine) by various cholinesterases

M E GRELIS et al. Br J Pharmacol Chemother. 1957 Sep.

Abstract

Several choline esters, including the imidazoleacryloyl and imidazolepropionyl compounds, have been hydrolysed by cholinesterases from various sources. The imidazolepropionyl ester was metabolized by cholinesterases obtained from human plasma, ox spleen, ox serum, and guinea-pig liver, but not by rat liver or bovine red cell cholinesterase. It is suggested the imidazolepropionylcholine or a closely related ester might be the natural substrate for "non-specific" cholinesterase.

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References

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    1. Nature. 1955 Oct 22;176(4486):783-4 - PubMed
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