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Case Reports
. 1992 May;31(5):351-3.
doi: 10.1093/rheumatology/31.5.351.

Fatal neutropenic enterocolitis associated with sulphasalazine therapy for rheumatoid arthritis

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Case Reports

Fatal neutropenic enterocolitis associated with sulphasalazine therapy for rheumatoid arthritis

K Chakravarty et al. Br J Rheumatol. 1992 May.

Abstract

Neutropenia is a recognized complication of sulphasalazine therapy in patients with rheumatoid arthritis. It is usually mild, transient and rarely associated with serious sequelae. We describe a patient with rheumatoid arthritis who developed fatal neutropenic enterocolitis complicated by tracheo-oesophageal fistula following treatment with sulphasalazine.

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