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Review
. 1992 May;17(5):191-6.
doi: 10.1016/0968-0004(92)90265-b.

How antibodies block HIV infection: paths to an AIDS vaccine

Review

How antibodies block HIV infection: paths to an AIDS vaccine

S Putney. Trends Biochem Sci. 1992 May.

Abstract

We are beginning to understand the mechanism that envelope proteins of the human and simian immunodeficiency viruses use to gain entry into host cells. A vaccine that can elicit antibodies that bind to the viral epitopes involved in this process would thereby prevent HIV infection. This article outlines our progress in the development of possible candidates for AIDS vaccines.

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