doi: 10.1084/jem.107.5.633.
Adsorption and maturation of poliovirus in singly and multiply infected HeLa cells
- PMID: 13525575
- PMCID: PMC2136847
- DOI: 10.1084/jem.107.5.633
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Adsorption and maturation of poliovirus in singly and multiply infected HeLa cells
J Exp Med.
.
Abstract
Studies with polio-infected HeLa cells using cell disruption techniques during the early stages of infection have shown that: The inoculum of poliovirus adsorbed on HeLa cells is largely inactivated. Infective virus accumulates in a monolayer sheet of cells in advance of release into the medium. The eclipse period is shorter in multiply infected cells than in those infected with a single particle.
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