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Review
. 1992:4 Suppl 1:71-8.

Alzheimer's disease: relationship of cognition and behavior to neurochemistry

Affiliations
  • PMID: 1354507
Free article
Review

Alzheimer's disease: relationship of cognition and behavior to neurochemistry

P J Whitehouse. Int Psychogeriatr. 1992.
Free article

Abstract

Alzheimer's disease is characterized by loss of cells and synapses in specific neural systems. The development of more effective therapies will depend on understanding the relationships between this pathology and the cognitive and behavioral impairments. In this review, focusing primarily on work in our laboratory, we will examine both classic and neuropeptide neurotransmitter systems and will discuss conceptual and methodological problems in relating clinical and biological measures.

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