Review
doi: 10.1016/0300-9629(92)90714-2.
Ferret red cells: Na/Ca exchange and Na-K-Cl cotransport
Affiliations
- PMID: 1355025
- DOI: 10.1016/0300-9629(92)90714-2
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Review
Ferret red cells: Na/Ca exchange and Na-K-Cl cotransport
Comp Biochem Physiol Comp Physiol.
1992 Aug.
Abstract
The primary pathway for K influx in ferret red cells is the Na-K-Cl cotransporter and the primary pathway for Ca influx is the Na/Ca exchanger. This makes ferret red cells favorable models for the study of these two transport systems. The evidence that Na/Ca exchange is of primary importance for steady state cell volume regulation and the Na-K-Cl cotransport has a minor role is presented. The approaches to, and results of, the determination of the stoichiometry, of the mechanism, and of the regulation by ATP and Mg, for Na/Ca exchange is contrasted with that taken for Na-K-Cl cotransport.
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