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Clinical Trial
. 1992 Aug:161:254-7.
doi: 10.1192/bjp.161.2.254.

Risk for definite neuroleptic malignant syndrome. A prospective study in 223 consecutive in-patients

H Hermesh  1 , D Aizenberg, A Weizman, M Lapidot, C Mayor, H Munitz
Affiliations
Clinical Trial

Risk for definite neuroleptic malignant syndrome. A prospective study in 223 consecutive in-patients

H Hermesh et al. Br J Psychiatry. 1992 Aug.

Abstract

The occurrence of neuroleptic malignant syndrome (NMS) was studied prospectively in two series of consecutive psychiatric in-patients (n = 223). The first group (n = 120) suffered from schizophrenia and was treated only with haloperidol. The second group (n = 103) was treated with diverse neuroleptics. All patients were on a single antipsychotic agent with no anticholinergic drug as prophylaxis. The incidence of full NMS per admission and first neuroleptic exposure was 5/223 (2.2%). Patients with bipolar affective disorder and those treated with injections were significantly over-represented in the NMS group.

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Comment in

  • Neuroleptic malignant syndrome.
    Simmons P, Marcus EL. Simmons P, et al. Br J Psychiatry. 1992 Nov;161:722-3. doi: 10.1192/bjp.161.5.722c. Br J Psychiatry. 1992. PMID: 1422640 No abstract available.

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