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Review
. 1992 Feb-Mar;10(2-3):109-36.
doi: 10.1016/0731-7085(92)80019-j.

Biopharmacological data and high-performance liquid chromatographic analysis of 1,4-benzodiazepines in biological fluids: a review

L A Berrueta  1 , B Gallo, F Vicente
Affiliations
Review

Biopharmacological data and high-performance liquid chromatographic analysis of 1,4-benzodiazepines in biological fluids: a review

L A Berrueta et al. J Pharm Biomed Anal. 1992 Feb-Mar.

Abstract

A review with 123 references on the analysis of 1,4-benzodiazepines in biological samples using HPLC is presented. Some important physico-chemical and biopharmacological data for the development of analytical methods are collected. Different methods of sample pretreatment, chromatographic conditions and detection systems are discussed.

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