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. 1992;25(3):149-52.
doi: 10.1159/000118825.

The rabbit syndrome and antiparkinsonian medication in schizophrenic patients

Y Wada  1 , N Yamaguchi
Affiliations

The rabbit syndrome and antiparkinsonian medication in schizophrenic patients

Y Wada et al. Neuropsychobiology. 1992.

Abstract

Effects of antiparkinsonian medication on the rabbit syndrome (RS) and accompanying parkinsonian symptoms were studied in 5 schizophrenic inpatients receiving long-term antipsychotic medication. All patients showed early improvement of RS following additional treatment with trihexyphenidyl or biperiden, with a significant reduction in the RS score also observed. The improvement of RS paralleled improvement of the parkinsonian symptoms, with the score of the Simpson-Angus rating scale significantly reduced. Our data provide further evidence that the underlying mechanism of RS is similar to that of acute forms of drug-induced parkinsonism.

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