Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1958 Nov 1;108(5):753-72.
doi: 10.1084/jem.108.5.753.

Folinic acid and non-dialyzable materials in the nutrition of malaria parasites

W TRAGER

Folinic acid and non-dialyzable materials in the nutrition of malaria parasites

W TRAGER. J Exp Med. .

Abstract

The extracellular survival of the malaria parasite Plasmodium lophurae was favored on the 4th day of incubation in vitro by the presence in the medium of added folinic acid at a concentration of about 5 microg. per ml. The development of the human malaria parasite P. falciparum intracellularly in suspensions of human erythrocytes was better in a medium with a high than in one with a low concentration of folic acid. In the early extracellular development of P. lophurae in vitro erythrocyte extract could be partially replaced by certain yeast protein preparations and by a non-dialyzable fraction, free from hemoglobin, prepared from duck erythrocyte extract by means of starch electrophoresis.

PubMed Disclaimer

References

    1. J Gen Physiol. 1951 Sep;35(1):89-118 - PubMed
    1. J Exp Med. 1950 Oct 1;92(4):349-66 - PubMed
    1. Acta Trop. 1957;14(4):289-301 - PubMed
    1. J Exp Med. 1946 Nov 30;84(6):583-606 - PubMed
    1. Annu Rev Biochem. 1956;25:397-434 - PubMed