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Review
. 1992 Nov;74(5):692-7.
doi: 10.1016/0030-4220(92)90367-y.

Contraindications to vasoconstrictors in dentistry: Part III. Pharmacologic interactions

J P Goulet  1 , R Pérusse, J Y Turcotte
Affiliations
Review

Contraindications to vasoconstrictors in dentistry: Part III. Pharmacologic interactions

J P Goulet et al. Oral Surg Oral Med Oral Pathol. 1992 Nov.

Abstract

This article discusses the relative contraindications to the use of vasoconstrictor in patients currently medicated with tricyclic antidepressants, monoamine oxidase inhibitors, phenothiazines and beta-blockers. It reviews drug interactions and emphasizes potential detrimental systemic effects that epinephrine contained in local anesthetics can have when administered concomitantly with these drugs. Finally, special considerations are expressed concerning patients who abuse illicit drugs such as cocaine.

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