Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Nov;30(11):3005-8.
doi: 10.1128/jcm.30.11.3005-3008.1992.

Epidemiology of nosocomial acquisition of Candida lusitaniae

Affiliations

Epidemiology of nosocomial acquisition of Candida lusitaniae

V Sanchez et al. J Clin Microbiol. 1992 Nov.

Abstract

Candida species are important nosocomial pathogens; however, little is known about the epidemiology of Candida lusitaniae, an organism frequently resistant to amphotericin B. We evaluated 98 patients admitted to the bone marrow transplant and medical intensive care units of a tertiary-care hospital. Each patient with C. lusitaniae was matched with control patients. Restriction fragment analysis of DNA was used to determine strain relatedness. Seven patients (7.1%) with C. lusitaniae were identified; five acquired C. lusitaniae after admission to the study unit. All isolates were susceptible to amphotericin B. There were no differences between patients and controls with regard to duration of stay in the study unit, antibiotic administration, antifungal therapy, immunosuppressive therapy, catheter use, or underlying disease. Temporal and geographic clustering of five patients with identical strains occurred. No common source was identified. Restriction fragment analysis revealed a total of eight strains, and five patients shared one strain type. These results demonstrate exogenous acquisition of C. lusitaniae. The mechanism of acquisition is probably indirect contact transmission between patients.

PubMed Disclaimer

References

    1. J Infect Dis. 1986 Jun;153(6):1075-83 - PubMed
    1. J Infect Dis. 1986 Mar;153(3):416-30 - PubMed
    1. Br Med J (Clin Res Ed). 1985 Mar 9;290(6470):746-8 - PubMed
    1. South Med J. 1985 May;78(5):626-7 - PubMed
    1. J Clin Microbiol. 1984 Mar;19(3):412-6 - PubMed

Publication types

MeSH terms