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. 1958 Nov 25;4(6):727-30.
doi: 10.1083/jcb.4.6.727.

Staining of tissue sections for electron microscopy with heavy metals. II. Application of solutions containing lead and barium

M L WATSON

Staining of tissue sections for electron microscopy with heavy metals. II. Application of solutions containing lead and barium

M L WATSON. J Biophys Biochem Cytol. .

Abstract

Descriptions of three heavy metal stains and methods of application to tissue sections for electron microscopy are presented. Lead hydroxide stains rather selectively two types of particles in liver: those associated with the endoplasmic reticulum and containing ribonucleic acid and other somewhat larger particles. Barium hydroxide emphasizes certain bodies within vesicles of the Golgi region of hepatic cells. Alkalized lead acetate is useful as a general stain, as are also lead and barium hydroxides.

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References

    1. J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):355-60 - PubMed
    1. J Biophys Biochem Cytol. 1957 Nov 25;3(6):1017-22 - PubMed
    1. J Biophys Biochem Cytol. 1958 Mar 25;4(2):151-6 - PubMed
    1. J Biophys Biochem Cytol. 1958 May 25;4(3):345-8 - PubMed
    1. J Biophys Biochem Cytol. 1958 Jul 25;4(4):475-8 - PubMed