Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1958 Dec;13(4):498-500.
doi: 10.1111/j.1476-5381.1958.tb00245.x.

The difference in the metabolism of injected [14C]histamine in male and female rats

H WESTLING

The difference in the metabolism of injected [14C]histamine in male and female rats

H WESTLING. Br J Pharmacol Chemother. 1958 Dec.

Abstract

[(14)C]Histamine was injected subcutaneously in rats. The urine was collected for 24 hr. and analysed for [(14)C]histamine and its various metabolites. It was found that male rats excreted less unchanged [(14)C]histamine than female ones, the difference between the sexes existing also when the animals were treated with aminoguanidine. The cause of the sexual difference appeared to be that the male rats had a larger capacity to methylate histamine.

PubMed Disclaimer

References

    1. Am J Physiol. 1955 Jun;181(3):484-6 - PubMed
    1. Br J Pharmacol Chemother. 1958 Mar;13(1):44-51 - PubMed
    1. J Appl Physiol. 1956 Nov;9(3):481-3 - PubMed
    1. Acta Physiol Scand. 1957 Dec 7;41(2-3):217-28 - PubMed
    1. J Biol Chem. 1953 Dec;205(2):739-48 - PubMed

LinkOut - more resources