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. 1959 Mar 1;109(3):257-70.
doi: 10.1084/jem.109.3.257.

The relative importance of the capsule and the M-antigen in determining colony form of group A streptococci

A T WILSON

The relative importance of the capsule and the M-antigen in determining colony form of group A streptococci

A T WILSON. J Exp Med. .

Abstract

Evidence is presented showing that the surface configuration of Group A streptococcal colonies depends largely on whether or not the cocci form a capsule. Strains which form capsules during growth on agar produce mucoid or matt colonies. Strains that do not form capsules during growth on agar produce glossy colonies. Whether or not M antigen is formed by the growing cocci appears to have no direct effect on surface configuration of the colony, although there is an indirect and partial association between M production and the mucoid-matt variant state and between M deficiency and the glossy variant state.

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