Review
Pharmacology of antitumor agents from higher plants
- PMID: 136296
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Review
Pharmacology of antitumor agents from higher plants
Cancer Treat Rep.
1976 Aug.
Abstract
Some pharmacologic properties of nine antitumor agents from higher plants are described. The agents are vincristine, vinblastine the epiodophyllotoxin derivatives VM-26 and VP-16-213, maytansine, bruceantin, thalicarpine, camptothecin, and lapachol. When sufficient information is available, the agents are discussed with regard to their antitumor activity, mechanism of action, pharmacologic disposition, structure-activity relationships, and toxicity.
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