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. 1976 Dec;20(6):472-8.

Study of the priming effect of interferon in L cells. I. The primed interferon response and the kinetics of development of priming

I Rosztóczy
  • PMID: 13642

Study of the priming effect of interferon in L cells. I. The primed interferon response and the kinetics of development of priming

I Rosztóczy. Acta Virol. 1976 Dec.

Abstract

Interferon was detected one hour earlier, its production followed an enhanced pattern and became resistant to actinomycin D 30 minutes sooner in cultures primed by interferon pretreatment before stimulation by polyriboinosinic-polyribocytidylic acid than in unprimed cultures. The kinetics of development of the primed state was found to be a time and dose dependent phenomenon. The continuous presence of interferon during the pretreatment period was not required for the development of the primed state.

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