[Polycystic ovary disease: clinical picture, diagnosis and methods of therapy]

Abstract

The study presents clinical features of polycystic ovaria with an incidence analysis of certain symptoms relevant for the diagnosis. Essential hormone parameters are showed, used for basal status evaluation, as well as endocrinologic tests applied for the determination of the causes of the disease within differential diagnostic investigation. Besides, in the differential diagnosis, possible diseases which should be excluded when diagnosing polycystic ovaria are showed. In the therapeutic protocol the stress is given to the methods used for the treatment of increased body hair, menstrual disorders and for ovulation induction. In the treatment of increased body hair cosmetic and medicamentous therapies are showed. In the ovulation induction method the application of clomiphene citrate, glycocorticosteroids, human menopausal genadotropins and a pulsatile pump for LHRH, have been analyzed in details. Moreover recent experiences in ovulation induction using LHRH analog (buserelin) and somatostatin analog (SMS) 201-995) are reported. Medicamentous ovulation induction was compared with surgical methods used for the induction (wedge resection and ovarial electrocauterization) pointing to the advantages and disadvantages of each method.