Review
Application of crystallography to the design of antiviral agents
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- PMID: 1365526
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Review
Application of crystallography to the design of antiviral agents
Infect Agents Dis.
1992 Feb.
Abstract
A historical review of x-ray crystallography introduces basic concepts and describes the potential of this science to the rational design of antiviral agents. Following a brief introduction to the study of antiviral compounds that inhibit early stages of rhino- and enteroviral infections, the impact of structural studies on rational drug design is discussed in relation to known viral structures.
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