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Review
. 1991 Feb;9(2):53-8.
doi: 10.1016/0167-7799(91)90189-O.

Exponential amplification of nucleic acids: new diagnostics using DNA polymerases and RNA replicases

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Review

Exponential amplification of nucleic acids: new diagnostics using DNA polymerases and RNA replicases

P M Lizardi et al. Trends Biotechnol. 1991 Feb.

Abstract

Recent developments in DNA and RNA amplification technology are enabling the design of ultra-sensitive diagnostic assays for infectious diseases. The leading amplification technology is the polymerase chain reaction (PCR). An alternative approach, Q-beta amplification, also promises remarkable speed and precise quantification of assay results.

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