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Review
. 1991 Oct;2(5):674-81.
doi: 10.1016/0958-1669(91)90033-2.

Streptomyces: a host for heterologous gene expression

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Review

Streptomyces: a host for heterologous gene expression

M Brawner et al. Curr Opin Biotechnol. 1991 Oct.

Abstract

Streptomyces species offer many potential advantages as hosts for the expression and secretion of eukaryotic gene products. In this review we discuss the expression and localization signals that have been used to direct heterologous gene expression and the applications of these signals. Finally, we discuss future strategies aimed at increasing the capacity of this host for the high level production of biologically active eukaryotic gene products.

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