Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1992 Jan-Feb;10(1-2):52-5.
doi: 10.1016/0167-7799(92)90169-v.

Semi-automated solid-phase DNA sequencing

M Uhlén  1 , T Hultman, J Wahlberg, J Lundeberg, S Bergh, B Pettersson, A Holmberg, S Ståhl, T Moks
Affiliations
Review

Semi-automated solid-phase DNA sequencing

M Uhlén et al. Trends Biotechnol. 1992 Jan-Feb.

Abstract

Increasing the efficiency of DNA sequencing necessitates the development of systems which reduce the need for manual operations by integrating template preparation, sequencing reactions, product separation and detection. A semi-automated system, whereby PCR-amplified biotinylated genomic or plasmid DNA is immobilized on streptavidin-coated magnetic beads, has been developed.

PubMed Disclaimer

Publication types