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Review
. 2003 Dec;63(2):115-27.
doi: 10.1007/s00253-003-1432-2. Epub 2003 Sep 16.

Bacterial heme biosynthesis and its biotechnological application

N Frankenberg  1 , J Moser, D Jahn
Affiliations
Review

Bacterial heme biosynthesis and its biotechnological application

N Frankenberg et al. Appl Microbiol Biotechnol. 2003 Dec.

Abstract

Proteins carrying a prosthetic heme group are vital parts of bacterial energy conserving and stress response systems. They also mediate complex enzymatic reactions and regulatory processes. Here, we review the multistep biosynthetic pathway of heme formation including the enzymes involved and reaction mechanisms. Potential biotechnological implications are discussed.

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