Comparative Study
doi: 10.1007/BF00174201.
The effect of Pluronic F-68 on hybridoma cells in continuous culture
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- PMID: 1368501
- DOI: 10.1007/BF00174201
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Comparative Study
The effect of Pluronic F-68 on hybridoma cells in continuous culture
Appl Microbiol Biotechnol.
1992 Apr.
Abstract
The comparative effects of Pluronic on cell growth of hybridomas were studied. The addition of 0.05% Pluronic decreased the steady-state cell number in continuous culture by about 12% compared to a non-supplemented culture. In short-term experiments, results demonstrated a gradual decrease in cell number with increasing concentration of Pluronic. Such growth inhibition was found to be a result of lowering the rate of DNA synthesis.
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