doi: 10.1126/science.133.3467.1822.
Role for ganglionic norepinephrine in sympathetic synaptic transmission
- PMID: 13695783
- DOI: 10.1126/science.133.3467.1822
Item in Clipboard
Role for ganglionic norepinephrine in sympathetic synaptic transmission
Science.
.
Abstract
Transmission of nerve impulses in superior cervical sympathetic ganglia of cats and rabbits is markedly enhanced after reserpine-induced depletion of ganglionic norepinephrine. Transmission is also enhanced by administration of adrenergic blocking agents. In contrast, reserpine-induced release of ganglionic norepinephrine in animals pretreated with a monoamine oxidase inhibitor results in a pronounced depression of ganglionic transmission, which lasts until the ganglionic norepinephrine disappears. These results support the concept that norepinephrine in ganglia modulates the action of acetylcholine.
Similar articles
-
Transmission in sympathetic ganglia.Fed Proc. 1970 Nov-Dec;29(6):1913-8. Fed Proc. 1970. PMID: 4394851 Review. No abstract available.
-
Transmission in sympathetic ganglia.Anesthesiology. 1968 Jul-Aug;29(4):634-42. doi: 10.1097/00000542-196807000-00004. Anesthesiology. 1968. PMID: 4299215 Review. No abstract available.
-
On the pharmacology of autonomic ganglia.Arch Int Pharmacodyn Ther. 1972 Apr;196:Suppl 196:244+. Arch Int Pharmacodyn Ther. 1972. PMID: 4404132 Review. No abstract available.
-
Detachment of structurally intact nerve endings from chromatolytic neurones of rat superior cervical ganglion during the depression of synaptic transmission induced by post-ganglionic axotomy.J Physiol. 1975 Feb;245(1):91-135. doi: 10.1113/jphysiol.1975.sp010837. J Physiol. 1975. PMID: 165288 Free PMC article.
-
Dopamine as a synaptic transmitter and modulator in sympathetic ganglia: a different mode of synaptic action.Proc Natl Acad Sci U S A. 1970 Oct;67(2):667-73. doi: 10.1073/pnas.67.2.667. Proc Natl Acad Sci U S A. 1970. PMID: 4399739 Free PMC article.
Cited by
-
Site of adrenaline blockade in the superior cervical ganglion of the rabbit.J Physiol. 1971 Feb;213(1):107-17. doi: 10.1113/jphysiol.1971.sp009371. J Physiol. 1971. PMID: 4324983 Free PMC article.
-
SOME ACTIONS OF CENTRALLY ACTIVE AND OTHER DRUGS ON THE TRANSMISSION OF SINGLE NERVE IMPULSES THROUGH THE ISOLATED SUPERIOR CERVICAL GANGLION PREPARATION OF THE RABBIT.Br J Pharmacol Chemother. 1964 Oct;23(2):222-40. doi: 10.1111/j.1476-5381.1964.tb01582.x. Br J Pharmacol Chemother. 1964. PMID: 14228127 Free PMC article.
-
Studies on sympathetic mechanisms in isolated intestinal and vas deferens preparations.Br J Pharmacol Chemother. 1962 Aug;19(1):85-98. doi: 10.1111/j.1476-5381.1962.tb01429.x. Br J Pharmacol Chemother. 1962. PMID: 13867378 Free PMC article.
-
Functional reinnervation of cat sympathetic ganglia with splenic nerve homografts.Experientia. 1971 Jul;27(7):799-801. doi: 10.1007/BF02136873. Experientia. 1971. PMID: 5139498 No abstract available.
-
SLOW SYNAPTIC RESPONSES AND EXCITATORY CHANGES IN SYMPATHETIC GANGLIA.J Physiol. 1964 Oct;174(1):1-25. doi: 10.1113/jphysiol.1964.sp007471. J Physiol. 1964. PMID: 14228610 Free PMC article. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous
