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Review
. 1992 May;8(5):164-8.
doi: 10.1016/0168-9525(92)90218-s.

Molecular genetics of sex determination in C. elegans

P E Kuwabara  1 , J Kimble
Affiliations
Review

Molecular genetics of sex determination in C. elegans

P E Kuwabara et al. Trends Genet. 1992 May.

Abstract

Sexual fate in the nematode Caenorhabditis elegans is controlled by a group of genetically well-characterized genes. Several of these sex-determining genes have now been analysed at the molecular level. Transcriptional regulation is likely to control both commitment to a single sexual fate and maintenance of that decision; in addition, intercellular signalling appears to coordinate the sexual fates of cells throughout the animal to adopt a single sexual fate.

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