doi: 10.1016/0165-7992(92)90050-r.
Mutagenicity of pyrrolizidine alkaloids in the Salmonella typhimurium/mammalian microsome system
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- PMID: 1370983
- DOI: 10.1016/0165-7992(92)90050-r
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Mutagenicity of pyrrolizidine alkaloids in the Salmonella typhimurium/mammalian microsome system
Mutat Res.
1992 Feb.
Abstract
The mutagenicity of a series of pyrrolizidine alkaloids, and of extracts from several Italian Senecio species containing pyrrolizidine alkaloids, including S. inaequidens, S. fuchsii and S. cacaliaster, were tested using the Salmonella typhimurium/mammalian microsome system. Retrorsine, senecivernine, seneciphylline and the Senecio extracts showed a weakly mutagenic activity.
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