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. 1992 Feb;34(2):176-9.

Use of latex agglutination testing in diagnosing pediatric meningitis

S A Feuerborn  1 , W I Capps, J C Jones
Affiliations
  • PMID: 1371141

Use of latex agglutination testing in diagnosing pediatric meningitis

S A Feuerborn et al. J Fam Pract. 1992 Feb.

Abstract

Background: Latex agglutination (LA) tests are ordered frequently on cerebral spinal fluid (CSF) specimens obtained from pediatric patients to identify pathogenic bacteria as early as possible in an acute infection.

Methods: Six hundred ten LA tests were performed on 176 patients suspected of having meningitis.

Results: Five patients with meningitis had positive LA tests. We found that the CSF white blood cell (WBC) count, and differential were the best predictors of meningitis.

Conclusions: By limiting the use of LA tests to those patients having CSF with abnormal WBC counts or with positive Gram stains, the number of tests ordered would have been reduced. This practice would greatly reduce laboratory expense.

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