Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1961 May 1;113(5):831-44.
doi: 10.1084/jem.113.5.831.

A new mouse virus causing necrosis of the thymus in newborn mice

W P ROWE, W I CAPPS

A new mouse virus causing necrosis of the thymus in newborn mice

W P ROWE et al. J Exp Med. .

Abstract

A new mouse virus has been recovered from laboratory and wild mice. The agent induces a non-fatal disease in infant mice, characterized by acute massive necrosis of the thymic medulla and cortex, granulomatous reaction, and subsequent restoration of essentially normal architecture with scarring. Intranuclear inclusion bodies are produced. Virus may persist in tissues of convalescent mice for many months. Electron micrographs of acutely infected thymuses showed nuclear and cytoplasmic karyoannular particles and masses of parallel fibrils in nuclei.

PubMed Disclaimer

References

    1. J Biophys Biochem Cytol. 1956 Nov 25;2(6):725-41 - PubMed
    1. J Natl Cancer Inst. 1959 Nov;23:1123-35 - PubMed