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. 1961 Jan 6;133(3445):44-5.
doi: 10.1126/science.133.3445.44.

Excessive stimulation of salivary gland growth by isoproterenol

Excessive stimulation of salivary gland growth by isoproterenol

H SELYE et al. Science. .

Abstract

In the rat, chronic treatment with isoproterenol can cause a selective growth of the salivary glands to approximately five times their normal size within 17 days. This enlargement is principally due to mitotic proliferation and hypertrophy of the parenchymatous cells.

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