Review
doi: 10.1111/j.1432-1033.1992.tb16929.x.
Small RNA helices as substrates for aminoacylation and their relationship to charging of transfer RNAs
Affiliations
- PMID: 1375910
- DOI: 10.1111/j.1432-1033.1992.tb16929.x
Item in Clipboard
Review
Small RNA helices as substrates for aminoacylation and their relationship to charging of transfer RNAs
Eur J Biochem.
.
Free article
Abstract
RNA microhelices that reconstruct the acceptor stems of transfer RNAs can be aminoacylated. The anticodon-independent aminoacylation is sequence-specific and suggests a relationship between amino acids and nucleotide sequences which is different from that of the classical genetic code. The specific aminoacylation of RNA microhelices also suggests a highly differentiated adaptation of the structures of aminoacyl-tRNA synthetases to sequences in the acceptor stems of transfer RNAs.
Similar articles
-
Aminoacylation of RNA minihelices: implications for tRNA synthetase structural design and evolution.Crit Rev Biochem Mol Biol. 1993;28(4):309-22. doi: 10.3109/10409239309078438. Crit Rev Biochem Mol Biol. 1993. PMID: 7691478 Review.
-
RNA tetraloops as minimalist substrates for aminoacylation.Biochemistry. 1992 Jun 2;31(21):4931-6. doi: 10.1021/bi00136a002. Biochemistry. 1992. PMID: 1599917
-
Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.J Mol Biol. 2000 Jun 2;299(2):431-46. doi: 10.1006/jmbi.2000.3749. J Mol Biol. 2000. PMID: 10860750
-
An operational RNA code for amino acids and possible relationship to genetic code.Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):8763-8. doi: 10.1073/pnas.90.19.8763. Proc Natl Acad Sci U S A. 1993. PMID: 7692438 Free PMC article. Review.
-
RNA minihelices and the decoding of genetic information.FASEB J. 1991 May;5(8):2180-7. doi: 10.1096/fasebj.5.8.2022314. FASEB J. 1991. PMID: 2022314
Cited by
-
Aminoacylating urzymes challenge the RNA world hypothesis.J Biol Chem. 2013 Sep 13;288(37):26856-63. doi: 10.1074/jbc.M113.496125. Epub 2013 Jul 18. J Biol Chem. 2013. PMID: 23867455 Free PMC article.
-
RNA recognition by designed peptide fusion creates "artificial" tRNA synthetase.Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7471-5. doi: 10.1073/pnas.1332771100. Epub 2003 Jun 9. Proc Natl Acad Sci U S A. 2003. PMID: 12796515 Free PMC article.
-
The Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed.Biol Direct. 2014 Jun 14;9:11. doi: 10.1186/1745-6150-9-11. Biol Direct. 2014. PMID: 24927791 Free PMC article.
-
tRNA acceptor stem and anticodon bases form independent codes related to protein folding.Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7489-94. doi: 10.1073/pnas.1507569112. Epub 2015 Jun 1. Proc Natl Acad Sci U S A. 2015. PMID: 26034281 Free PMC article.
-
An operational RNA code for amino acids and variations in critical nucleotide sequences in evolution.J Mol Evol. 1995 May;40(5):531-6. doi: 10.1007/BF00166621. J Mol Evol. 1995. PMID: 7783226 Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
