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Review
. 1992 Jun;6(3):687-706.

Differentiation therapy

R L Paquette  1 , H P Koeffler
Affiliations
  • PMID: 1377195
Review

Differentiation therapy

R L Paquette et al. Hematol Oncol Clin North Am. 1992 Jun.

Abstract

A variety of compounds are able to induce myeloid leukemia cells to differentiate into morphologically and functionally mature cells. Vitamin D derivatives, retinoids, interferons, and polar-planar compounds are agents that demonstrate such activity in vitro and have been employed as therapy for the myelodysplastic syndromes.

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