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. 1961 Feb 1;113(2):451-65.
doi: 10.1084/jem.113.2.451.

The occurrence of two M antigens in certain group A streptococci related to type 14

G G WILEY, A T WILSON

The occurrence of two M antigens in certain group A streptococci related to type 14

G G WILEY et al. J Exp Med. .

Abstract

A strain of Group A streptococcus previously considered to belong to Type 14 was shown to have two immunologically distinct M antigens, designated Type 14 and Type 51. Most strains having the Type 14 M antigen were found to have also the Type 51 M antigen, and are considered to belong to Type 14-51. Four strains had the Type 51 M antigen without the Type 14 M antigen and one strain had the Type 14 M antigen without the Type 51 M antigen. The failure of a variant to produce the known M antigen of the parent strain does not necessarily mean that the strain is M(-), because a second M antigen may be present as was the case in several strains described here.

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