Rapid induction of allergic encephalomyelitis in rats without the use of mycobacteria
- PMID: 13798502
- DOI: 10.1126/science.131.3411.1448
Rapid induction of allergic encephalomyelitis in rats without the use of mycobacteria
Abstract
Rats, in contrast to certain other species of animals reported, have a striking capacity to develop allergic encephalomyelitis within 2 to 3 weeks following one injection of spinal cord antigen combined with Freund's incomplete adjuvant-that is, adjuvant prepared without addition of killed mycobacteria.
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