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. 1960 May 13;131(3411):1448.
doi: 10.1126/science.131.3411.1448.

Rapid induction of allergic encephalomyelitis in rats without the use of mycobacteria

Rapid induction of allergic encephalomyelitis in rats without the use of mycobacteria

J BELL et al. Science. .

Abstract

Rats, in contrast to certain other species of animals reported, have a striking capacity to develop allergic encephalomyelitis within 2 to 3 weeks following one injection of spinal cord antigen combined with Freund's incomplete adjuvant-that is, adjuvant prepared without addition of killed mycobacteria.

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