Neurotransmitter transporters (plus): a promising new gene family
- PMID: 1381123
- DOI: 10.1016/0166-2236(92)90068-j
Neurotransmitter transporters (plus): a promising new gene family
Abstract
Neurotransmitter transporter genes encode proteins with 12 putative transmembrane regions, which mediate Na(+)-dependent reaccumulation of released neurotransmitters into presynaptic terminals and are the sites of action of important abused and therapeutic drugs. Studies of these genes show promise for improving our understanding of transport mechanisms and modes of drug action, and may even uncover previously unanticipated neurotransmitters.
Comment in
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Are neurotransmitter carriers cell-specific markers?Trends Neurosci. 1992 Dec;15(12):482; author reply 483-4. doi: 10.1016/0166-2236(92)90093-n. Trends Neurosci. 1992. PMID: 1282744 No abstract available.
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Are neurotransmitter carriers cell-specific markers?Trends Neurosci. 1992 Dec;15(12):482-3; author reply 483-4. doi: 10.1016/0166-2236(92)90094-o. Trends Neurosci. 1992. PMID: 1282745 No abstract available.
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Are neurotransmitter carriers cell-specific markers?Trends Neurosci. 1992 Dec;15(12):483; author reply 483-4. doi: 10.1016/0166-2236(92)90096-q. Trends Neurosci. 1992. PMID: 1282746 No abstract available.
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